concept

Diabetes mellitus

Diabetes mellitus is a diagnostic term for a group of disorders characterized by abnormal glucose homeostasis resulting in elevated blood sugar. It is among the most common of chronic disorders, affecting up to 5–10% of the adult population of the Western world. The prevalence of diabetes is increasing dramatically; it has been estimated that the worldwide prevalence will increase by more than 50% between the years 2000 and 2030 (Wild et al., 2004). It is clearly established that diabetes mellitus is not a single disease, but a genetically heterogeneous group of disorders that share glucose intolerance in common. The concept of genetic heterogeneity (i.e. that different genetic and/or environmental etiologic factors can result in similar phenotypes) has significantly altered the genetic analysis of this common disorder.

Ref:
L.J. Raffel, M.O. Goodarzi, Diabetes Mellitus, Reference Module in Biomedical Sciences, Elsevier, 2014, , ISBN 9780128012383, https://doi.org/10.1016/B978-0-12-801238-3.05558-6.

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Added on Jun 25, 2022 by Barbara Van De Keer
Edited on Aug 17, 2022 by Barbara Van De Keer

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