concept

TLR4 (Toll-like receptor 4)

The stimulation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) induces the release of critical proinflammatory cytokines that are necessary to activate potent immune responses.

Ref:
Lu YC, Yeh WC, Ohashi PS. LPS/TLR4 signal transduction pathway. Cytokine. 2008 May;42(2):145-151. doi: 10.1016/j.cyto.2008.01.006. Epub 2008 Mar 4. PMID: 18304834.

20 confidence points
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Added on Nov 6, 2022 by Barbara Van De Keer

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